1.       Allanore Y, Meune C, Vonk MC, Airo P, Hachulla E, Caramaschi P, Riemekasten, G, Cozzi F, Beretta L, Derk CT, Komócsi A, Farge D, Balbir A, Riccieri V, Distler O, Chialà A, Papa ND, Simic KP, Ghio M, Stamenkovic B, Rednic S, Host N, Pellerito, R, Zegers E, Kahan A, Walker UA, Matucci-Cerinic M; EUSTAR co-authors. Prevalence and factors associated with left ventricular dysfunction in the EULAR Scleroderma Trial and Research group (EUSTAR) database of patients with systemic sclerosis. Ann Rheum Dis. 2010; 69(1):218-21. PMID: 19279015

2.       Avouac J, Walker U, Tyndall A, Kahan A, Matucci-Cerinic M, Allanore Y; EUSTAR, Miniati I, Muller A, Iannone F, Distler O, Becvar R, Sierakowsky S, Kowal-Bielecka O, Coelho P, Cabane J, Cutolo M, Shoenfeld Y, Valentini G, Rovensky J, Riemekasten G, Vlachoyiannopoulos P, Caporali R, Jiri S, Inanc M, Zimmermann Gorska I, Carreira P, Novak S, Czirjak L, Oliveira Ramos F, Jendro M, Chizzolini C, Kucharz EJ, Richter J, Cozzi F, Rozman B, Mallia CM, Gabrielli A, Farge D, Kiener HP, Schöffel D, Airo P, Wollheim F, Martinovic D, Trotta F, Jablonska S, Reich K, Bombardieri S, Siakka P, Pellerito R, Bambara LM, Morovic-Vergles J, Denton C, Hinrichs R, Van den Hoogen F, Damjanov N, Kötter I, Ortiz V, Heitmann S, Krasowska D, Seidel M, Hasler P, Van Laar JM, Kaltwasser JP, Foeldvari I, Juan Mas A, Bajocchi G, Wislowska M, Pereira Da Silva JA, Jacobsen S, Worm M, Graniger W, Kuhn A, Stankovic A, Cossutta R, Majdan M, Damjanovska Rajcevska L, Tikly M, Nasonov EL, Steinbrink K, Herrick A, Müller-Ladner U, Dinc A, Scorza R, Sondergaard K, Indiveri F, Nielsen H, Szekanecz Z, Silver RM, Antivalle M, Espinosa IB, García de la Pena Lefebvre P, Midtvedt O, Launay D, Valesini F, Tuvik P, Ionescu RM, Del Papa N, Pinto S, Wigley F, Mihai C, Sinziana Capranu M, Sunderkötter C, Jun JB, Alhasani S, Distler JH, Ton E, Soukup T, Seibold J, Zeni S, Nash P, Mouthon L, De Keyser F, Duruöz MT, Cantatore FP, Strauss G, von Mülhen CA, Pozzi MR, Eyerich K, Szechinski J, Keiserman M, Houssiau FA, Román-Ivorra JA, Krummel-Lorenz B, Aringer M, Westhovens R, Bellisai F, Mayer M, Stoeckl F, Uprus M, Volpe A, Buslau M, Yavuz S, Granel B, Valderílio Feijó A, Del Galdo F, Popa S, Zenone T, Ricardo Machado X, Pileckyte M, Stebbings S, Mathieu A, Tulli A, Tourinho T, Souza R, Acayaba de Toledo R, Stamp L, Solanki K, Veale D, Francisco Marques Neto J, Bagnato GF, Loyo E, Toloza S, Li M, Ahmed Abdel Atty Mohamed W, Cobankara V, Olas J, Salsano F, Oksel F, Tanaseanu CM, Foti R, Ancuta C, Vonk M, Caramashi P, Beretta L, Balbir A, Chiàla A, Pasalic Simic K, Ghio M, Stamenkovic B, Rednic S, Host N, Pellerito R, Hachulla E, Furst DE. Characteristics of joint involvement and relationships with systemic inflammation in systemic sclerosis: results from the EULAR Scleroderma Trial and Research Group (EUSTAR) database. J Rheumatol. 2010; 37(7):1488-501. PMID: 20551097

3.       Beretta L, Santaniello A, Cappiello F, Chawla NV, Vonk MC, Carreira PE, Allanore Y, Popa-Diaconu DA, Cossu M, Bertolotti F, Ferraccioli G, Mazzone A, Scorza R. Development of a five-year mortality model in systemic sclerosis patients by different analytical approaches. Clin Exp Rheumatol. 2010 Mar-Apr;28(2 Suppl 58):S18-27. PMID: 20804663

4.       Beretta L, Santaniello A, van Riel PL, Coenen MJ, Scorza R. Survival dimensionality reduction (SDR): development and clinical application of an innovative approach to detect epistasis in presence of right-censored data. BMC Bioinformatics. 2010; 11:416. PMID: 20691091

5.       Blom M, Kievit W, Kuper HH, Jansen TL, Visser H, den Broeder AA, Brus HL, van de Laar MA, van Riel PL. The frequency and effectiveness of dose increase of adalimumab, etanercept and infliximab in daily clinical practice: results of the Dutch Rheumatoid Arthritis Monitoring registry. Arthritis Care Res (Hoboken). 2010; 62(9):1335-41. PMID: 20506128.

6.       Coates LC, Fransen J, Helliwell PS. Defining minimal disease activity in psoriatic arthritis: a proposed objective target for treatment. Ann Rheum Dis. 2010; 69(1):48-53.. PMID: 19147615.

7.       Coenen MJ, Enevold C, Barrera P, Schijvenaars MM, Toonen EJ, Scheffer H, Padyukov L, Kastbom A, Klareskog L, Barton A, Kievit W, Rood MJ, Jansen TL, Swinkels D, van Riel PL, Franke B, Bendtzen K, Radstake TR. Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome. PLoS One. 2010 ; 5(12):e14326. PMID: 21179534

8.       Dawidowicz K, Allanore Y, Guedj M, Pierlot C, Bombardieri S, Balsa A, Westhovens R, Barrera P, Alves H, Teixeira VH, Petit-Teixeira E, van de Putte L, van Riel P, Prum B, Bardin T, Meyer O, Cornélis F, Dieudé P; for ECRAF. The interferon regulatory factor 5 gene confers susceptibility to rheumatoid arthritis and influences its erosive phenotype. Ann Rheum Dis. 201; 70(1):117-21. PMID: 20980283 

9.       de Brouwer SJ, Kraaimaat FW, Sweep FC, Creemers MC, Radstake TR, van Laarhoven AI, van Riel PL, Evers AW. Experimental stress in inflammatory rheumatic diseases: a review of psychophysiological stress responses. Arthritis Res Ther. 2010; 12(3):R89. PMID: 2047802 

10.   Dougados M, Wells G, Schmidely N, Le Bars M, van Riel P, Aletaha D, Schiff M, Smolen J. Evaluation of disease activity assessments in patients with rheumatoid arthritis and an inadequate response to anti-TNF therapy: analyses of abatacept clinical trial data. Clin Exp Rheumatol. 2010; 28(2):259-60. PMID: 20483050. 

11.   Enevold C, Radstake TR, Coenen MJ, Fransen J, Toonen EJ, Bendtzen K, van Riel PL. Multiplex Screening of 22 Single-Nucleotide Polymorphisms in 7 Toll-like Receptors: An Association Study in Rheumatoid Arthritis. J Rheumatol. 2010; 37(5):905-10 PMID: 20194452 .  

12.   Fluit  CRMG, Bolhuis S, Grol R, Laan R, Wensen, M. Assessing the quality of clinical teachers. A systematic review of content and quality of questionnaires for assessing clinical teachers. J. Gen Internal Med 2010; 25(12):1337-45. PMID: 20703952. 

13.   Fransen J, Visser K, van Dongen H, Huizinga T, van Riel P, van der Heijde D. Validity of the disease activity score in undifferentiated arthritis. Arthritis Care Res (Hoboken). 2010; 62(10): 1302-8. PMID: 20506371. 

14.   Furst DE, Keystone EC, Fleischmann R, Mease P, Breedveld FC, Smolen JS, Kalden, JR, Braun J, Bresnihan B, Burmester GR, De Benedetti F, Dörner T, Emery P, Gibofsky A, Kavanaugh A, Kirkham B, Schiff MH, Sieper J, Singer N, Van Riel PL, Weinblatt ME, Weisman MH, Winthrop K. Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2009. Ann Rheum Dis. 2010; 69 Suppl 1:i2-29. PMID: 19995740. 

15.   Gaujoux-Viala C, Smolen JS, Landewé R, Dougados M, Kvien TK, Mola EM, Scholte-Voshaar M, van Riel P, Gossec L. Current evidence for the management of rheumatoid arthritis with synthetic disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis. 2010; 69(6):1004-9. PMID: 19796918.  

16.   Hargardóttir H, van Helvoort HA, Vonk MC, van den Hoogen FH, Dekhuijzen PN, Heijdra YF. Exercise in systemic sclerosis intensifies systemic inflammation and oxidative stress. Scand J Rheumatol. 2010;39(1):63-70. PMID: 20132073. 

17.   Helmich E, Derksen E, Prevoo M, Laan R, Bolhuis S, Koopmans R. Medical students' professional identity development in an early nursing attachment. Med Educ. 2010 ;44(7):674-82. PMID: 20636586 

18.   Janssens HJ, Janssen M, van de Lisdonk EH, Fransen J, van Riel PL, van Weel C. Limited validity of the American College of Rheumatology criteria for classifying patients with gout in primary care. Ann Rheum Dis. 2010;69(6):1255-6PMID: 19910298. 

19.   Janssen HJ, Fransen J, van de Lisdonk EH, van Riel PL, van Weel C, Janssen M. A diagnostic rule for acute gouty arthritis in primary care without joint fluid analysis. Arch Intern Med 2010; 170(13): 1120-6. 

20.   Kievit W, van Hulst L, van Riel PL, Fraenkel L. Factors that influence rheumatologists' decisions to escalate care in rheumatoid arthritis: results from a choice-based conjoint analysis. Arthritis Care Res (Hoboken). 2010 ;62(6):842-7.PMID: 20535795 

21.   Kievit W, Hendrikx J, Stalmeier PF, van de Laar MA, Van Riel PL, Adang EM. The relationship between change in subjective outcome and change in disease: a potential paradox. Qual Life Res. 2010: 19: 985-994. PMID: 20454862 

22.   Kievit W, Fransen J, Adang EM, den Broeder AA, Bernelot Moens HJ, Visser H, van de Laar MA, van Riel PL. Long-term effectiveness and safety of TNF-blocking agents in daily clinical practice: results from the Dutch Rheumatoid Arthritis Monitoring register. Rheumatology (Oxford). 2010 50(1):196-203. PMID: 21078625  

23.   Kroot JJ, Laarakkers CM, Geurts-Moespot AJ, Grebenchtchikov N, Pickkers P, van Ede AE, Peters HP, van Dongen-Lases E, Wetzels JF, Sweep FC, Tjalsma H, Swinkels DW.Immunochemical and mass-spectrometry-based serum hepcidin assays for iron metabolism disorders. Clin Chem. 2010 ;56(10):1570-9. PMID: 20739637 

24.   Laan RFJM, Leunissen RRM, van Herwaarden CLA. The 2009 framework for undergraduate medical education in the Netherlands. Tijdschr Med Onderwijs 2010; 29(1): 10-15  

25.   Ng CT, Radovits BJ, Kievit W, Fransen J, van Riel PL, FitzGerald O, Veale DJ, Bresnihan B. Unregulated prescribing of anti-tumour necrosis factor agents does not mean inappropriate prescribing. Ann Rheum Dis. 2010 ;69(1):313-4. PMID: 20007623. 

26.   Pavy S, Toonen EJ, Miceli-Richard C, Barrera P, van Riel PL, Criswell LA, Mariette X, Coenen MJ. Tumour necrosis factor alpha -308G->A polymorphism is not associated with response to TNFalpha blockers in Caucasian patients with rheumatoid arthritis: systematic review and meta-analysis. Ann Rheum Dis. 2010 ;69(6):1022-8. 

27.   Plantinga TS, Fransen J, Takahashi N, Stienstra R, van Riel PL, van den Berg WB, Netea MG, Joosten LA. Functional consequences of DECTIN-1 early stop codon polymorphism Y238X in rheumatoid arthritis. Arthritis Res Ther. 2010 ;12(1):R26. PMID: 20158887. 

28.   Radovits BJ, Fransen J, Al Shamma S, Eijsbouts AM, van Riel PL, Laan RF. Excess mortality emerges after 10 years in an inception cohort of early rheumatoid arthritis. Arthritis Care Res (Hoboken). 2010; 62(3):362-70. PMID: 20391482. 

29.   Radstake TR, Gorlova O, Rueda B, Martin JE, Alizadeh BZ, Palomino-Morales R, Coenen MJ, Vonk MC, Voskuyl AE, Schuerwegh AJ, Broen JC, van Riel PL, van ’t Slot R, Italiaander A, Ophoff RA, Riemekasten G, Hunzelmann N, Simeon CP, Ortego-Centeno N, González-Gay MA, González-Escribano MF; Spanish Scleroderma Group, Airo P, van Laar J, Herrick A, Worthington J, Hesselstrand R, Smith V, de Keyser F, Houssiau F, Chee MM, Madhok R, Shiels P, Westhovens R, Kreuter A, Kiener H, de Baere E, Witte T, Padykov L, Klareskog L, Beretta L, Scorza R, Lie BA, Hoffmann-Vold AM, Carreira P, Varga J, Hinchcliff M, Gregersen PK, Lee AT, Ying J, Han Y, Weng SF, Amos CI, Wigley FM, Hummers L, Nelson JL, Agarwal SK, Assassi S, Gourh P, Tan FK, Koeleman BP, Arnett FC, Martin J, Mayes MD. Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet. 2010;42(5):426-9. PMID: 20383147. 

30.   Reinders MK, Jansen TL. New advances in the treatment of gout: review of pegloticase. Ther Clin Risk Manag. 2010; 6:543-50.PMID: 21127695 

31.   Roy S, Jansen TL, Knoester J. Structural classification of the amide I sites of a beta-hairpin with isotope label 2DIR spectroscopy. Phys Chem Chem Phys. 2010;12(32):9347-57. PMID: 20596553 

32.   Rueda B, Gourh P, Broen J, Agarwal SK, Simeon C, Ortego-Centeno N, Vonk MC, Coenen M, Riemekasten G, Hunzelmann N, Hesselstrand R, Tan FK, Reveille JD, Assassi S, Garcia-Hernandez FJ, Carreira P, Camps M, Fernandez-Nebro A, Garcia de la Peña P, Nearney T, Hilda D, Gónzalez-Gay MA, Airo P, Beretta L, Scorza R, Radstake TR, Mayes MD, Arnett FC, Martin J. BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in Caucasians. Ann Rheum Dis. 2010; 69(4): 700-5. PMID: 19815934. 

33.   Schipper LG, van Hulst LT, Grol R, van Riel PL, Hulscher ME, Fransen J. Meta-analysis of tight control strategies in rheumatoid arthritis: protocolized treatment has additional value with respect to the clinical outcome. Rheumatology (Oxford). 2010; 49(11): 2154-64. PMID: 20671022 

34.   Schipper LG, Fransen J, den Broeder AA, Van Riel PL. Time to achieve remission determines time to be in remission. Arthritis Res Ther. 2010;12(3):R97. PMID: 20487520 

35.   Smith AW, Lessing J, Ganim Z, Peng CS, Tokmakoff A, Roy S, Jansen TL, Knoester J. Melting of a beta-hairpin peptide using isotope-edited 2D IR spectroscopy and simulations. J Phys Chem B. 2010; 114(34):10913-24. PMID: 20690697 

36.   Schmitz MW, de Waal Malefijt MC, van Heereveld HA. Resection arthroplasty for luxation of the manubrio-sternal joint in rheumatoid arthritis--a case report. Acta Orthop. 2010; 81(3):405-6. PMID: 20367413 

37.   Smolen JS, Landewé R, Breedveld FC, Dougados M, Emery P, Gaujoux-Viala C, Gorter S, Knevel R, Nam J, Schoels M, Aletaha D, Buch M, Gossec L, Huizinga T, Bijlsma JW, Burmester G, Combe B, Cutolo M, Gabay C, Gomez-Reino J, Kouloumas M, Kvien TK, Martin-Mola E, McInnes I, Pavelka K, van Riel P, Scholte M, Scott DL, Sokka T, Valesini G, van Vollenhoven R, Winthrop KL, Wong J, Zink A, van der Heijde D. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann Rheum Dis. 2010; 69(6):964-75. PMID: 20444750  

38.   Smulders E, Weerdesteyn V, Groen BE, Duysens J, Eijsbouts A, Laan R, van Lankveld W. Efficacy of a short multidisciplinary falls prevention program for elderly persons with osteoporosis and a fall history: a randomized controlled trial. Arch Phys Med Rehabil. 2010; 91(11):1705-11.PMID: 21044715 

39.   Stahl EA, Raychaudhuri S, Remmers EF, Xie G, Eyre S, Thomson BP, Li Y, Kurreeman FA, Zhernakova A, Hinks A, Guiducci C, Chen R, Alfredsson L, Amos CI, Ardlie KG; BIRAC Consortium, Barton A, Bowes J, Brouwer E, Burtt NP, Catanese JJ, Coblyn J, Coenen MJ, Costenbader KH, Criswell LA, Crusius JB, Cui J, de Bakker PI, De Jager PL, Ding B, Emery P, Flynn E, Harrison P, Hocking LJ, Huizinga TW, Kastner DL, Ke X, Lee AT, Liu X, Martin P, Morgan AW, Padyukov L, Posthumus MD, Radstake TR, Reid DM, Seielstad M, Seldin MF, Shadick NA, Steer S, Tak PP, Thomson W, van der Helm-van Mil AH, van der Horst-Bruinsma IE, van der Schoot CE, van Riel PL, Weinblatt ME, Wilson AG, Wolbink GJ, Wordsworth BP; YEAR Consortium, Wijmenga C, Karlson EW, Toes RE, de Vries N, Begovich AB, Worthington J, Siminovitch KA, Gregersen PK, Klareskog L, Plenge RM.. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.. Nat Genet. 2010;42(6):508-14.PMID: 20453842

40.   Tyndall AJ, Bannert B, Vonk M, Airò P, Cozzi F, Carreira PE, Bancel DF, Allanore Y, Müller-Ladner U, Distler O, Iannone F, Pellerito R, Pileckyte M, Miniati I, Ananieva L, Gurman AB, Damjanov N, Mueller A, Valentini G, Riemekasten G, Tikly M, Hummers L, Henriques MJ, Caramaschi P, Scheja A, Rozman B, Ton E, Kumánovics G, Coleiro B, Feierl E, Szucs G, Von Mühlen CA, Riccieri V, Novak S, Chizzolini C, Kotulska A, Denton C, Coelho PC, Kötter I, Simsek I, de la Pena Lefebvre PG, Hachulla E, Seibold JR, Rednic S, Stork J, Morovic-Vergles J, Walker UA. Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database. Ann Rheum Dis. 2010 ;69(10):1809-15. PMID: 20551155 

41.   van Bon L, Popa C, Huijbens R, Vonk M, York M, Simms R, Hesselstrand R, Wuttge DM, Lafyatis R, Radstake TR. Distinct evolution of TLR-mediated dendritic cell cytokine secretion in patients with limited and diffuse cutaneous systemic sclerosis. Ann Rheum Dis. 2010; 69(8):1539-47. PMID: 20498209 

42.   van der Giesen FJ, van Lankveld W, Hopman-Rock M, de Jong Z, Munneke M, Hazes JM, van Riel PL, Peeters AJ, Ronday HK, Vlieland TP. Exploring the public health impact of an intensive exercise program for patients with rheumatoid arthritis: a dissemination and implementation study. Arthritis Care Res (Hoboken). 2010; 62(6):865-72. PMID: 20535798 

43.   van der Maas A, van den Ende C, van Eerd J, Fransen J, den Broeder A. The use of different methods for rapid determination of the ESR induces DAS28 misclassification in clinical practice. Clin Exp Rheumatol. 2010 28(4):477-82. PMID: 20598225 

44.   van Hoogmoed D, Fransen J, Bleijenberg G, van Riel P. Physical and psychosocial correlates of severe fatigue in rheumatoid arthritis. Rheumatology (Oxford). 2010 49(7):1294-302. PMID: 20353956.  

45.   van Hulst LT, Creemers MC, Fransen J, Li LC, Grol R, Hulscher ME, van Riel PL. How to improve DAS28 use in daily clinical practice?--a pilot study of a nurse-led intervention. Rheumatology (Oxford). 2010; 49(4):741-8. PMID: 20083537. 

46.   van Koulil S, van Lankveld W, Kraaimaat FW, van Helmond T, Vedder A, van Hoorn H, Donders R, de Jong AJ, Haverman JF, Korff KJ, van Riel PL, Cats HA, Evers AW. Tailored cognitive-behavioral therapy and exercise training for high-risk fibromyalgia patients. Arthritis Care Res (Hoboken). 2010; 62(10):1377-85. PMID: 20521308 

47.   van Koulil S, van Lankveld W, Kraaimaat FW, van Riel PL, Evers AW. Risk factors for longer term psychological distress in well-functioning fibromyalgia patients: a prospective study into prognostic factors.Patient Educ Couns. 2010; 80(1):126-9.  

48.   Weersma RK, Crusius JBA, Roberts RL, Koeleman BPC, Palomino-Morales R, Wolfkamp S, Hollis-Moffatt JE, Festen EAM, Meisneris S, Heijmans R, Nobel CL, Geary RB, Barclay ML, Gómez-Garce M, Lopez-Nevot MA, Nieto A, Rodrigo L, Radstake TRDJ, van Bodegraven AA, Wijmenga C, Merriman TR, Stokkers PCF, Salvador Pena A, Marin J, Alizadeh BZ. Association of FcgR2a, but not FcgR3a, with inflammatory bowel diseases across three Caucasian populations. Inflamm Bowel Dis. 2010; 16(12):2080-9. doi: 10.1002/ibd.21342. PMID: 20848524

49.   Alizadeh BZ, Broen J, Rueda B, Hesselstrand R, Wuttge D, Simeon C, Ortego-Centeno N, Gonzalez-Gay MA, Pros A, Herrick A, Worthington J, Denton C, Fonseca C, Riemekasten G, Vonk MC, van den Hoogen F, Guiducci S, Matucci-Cerinic M, Scorza R, Beretta L, Airó P, Coenen M, Martin J, Koeleman BP, Radstake TR; EUSTAR. Functional Variants of Fc Gamma Receptor (FCGR2A) and FCGR3A Are Not Associated with Susceptibility to Systemic Sclerosis in a Large European Study (EUSTAR). J Rheumatol. 2010; 37(8):1673-9. PMID: 20551103

50.   Bhansing KJ, van Bon L, Janssen M, Radstake TR. Gout: a clinical syndrome illustrated and discussed. Neth J Med. 2010; 68(9): 352-9. PMID: 20876915. 

51.   Broen JCA, Wolvers-Tettero ILM, Geurts-van Bon L, Vonk MC, Coenen MJH, Lafyatis R, Radstake TRDJ, Langerak AW. Skewed X chromosomal inactivation impacts T regulatory cell function in systemic sclerosis. Ann Rheum Dis. 2010 ;69(12):2213-6. PMID: 20699236 

52.   Gourh P, Agarwal SK, Martin E, Divecha D, Rueda B, Bunting H, Assassi S, Paz G, Shete S, McNearney T, Draeger H, Reveille JD, Radstake TR, Simeon CP, Rodriguez L, Vicente E, Gonzalez-Gay MA, Mayes MD, Tan FK, Martin J, Arnett FC. Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations. J Autoimmun. 2010;34(2):155-62 

53.   Kurreeman FA, Goulielmos GN, Alizadeh BZ, Rueda B, Houwing-Duistermaat J, Sanchez E, Bevova M, Radstake TR, Vonk MC, Galanakis E, Ortego N, Verduyn W, Zervou MI, Roep BO, Dema B, Espino L, Urcelay E, Boumpas DT, van den Berg LH, Wijmenga C, Koeleman BP, Huizinga TW, Toes RE, Martin J; AADEA Group; SLEGEN Consortium. The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases. Ann Rheum Dis. 2010;69(4):696-9. PMID: 19433411. 

54.   Martín JE, Alizadeh BZ, González-Gay MA, Balsa A, Pascual-Salcedo D, Fernández-Gutiérrez B, Raya E, Franke L, van't Slot R, Coenen MJ, van Riel P, Radstake TR, Koeleman BP, Martín J. Identification of the oxidative stress-related gene MSRA as a rheumatoid arthritis susceptibility locus by genome-wide pathway analysis. Arthritis Rheum. 2010;62(11):3183-90. doi:  1002/art.27648. PMID: 20617525 

55.   McKinney C, Fanciulli M, Merriman ME, Phipps-Green A, Alizadeh BZ, Koeleman BP, Dalbeth N, Gow PJ, Harrison AA, Highton J, Jones PB, Stamp LK, Steer S, Barrera P, Coenen MJ, Franke B, van Riel PL, Vyse TJ, Aitman TJ, Radstake TR, Merriman TR. Association of variation in Fc{gamma} receptor 3B gene copy number with rheumatoid arthritis in Caucasian samples. Ann Rheum Dis. 2010 ;69(9):1711-6. PMID: 20472591 

56.   Coenen MJ, Enevold C, Barrera P, Schijvenaars MM, Toonen EJ, Scheffer H, Padyukov L, Kastbom A, Klareskog L, Barton A, Kievit W, Rood MJ, Jansen TL, Swinkels D, van Riel PL, Franke B, Bendtzen K, Radstake TR. Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome. PLoS One. 2010 ; 5(12): e14326. PMID: 21179534. 

57.   Arntz OJ, Geurts J, Veenbergen S, Bennink MB, van den Brand BT, Abdollahi-Roodsaz S, van den Berg WB, van de Loo FA. A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis. Arthritis Res Ther. 2010;12(2):R61. Epub 2010 Apr 6. PubMed PMID: 20370892; PubMed Central PMCID: PMC2888212. 

58.   Blom AB, van Lent PL, van der Kraan PM, van den Berg WB. To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy. Curr Drug Targets. 2010 May;11(5):620-9. Review. PubMed PMID: 20199388. 

59.   Bondeson J, Blom AB, Wainwright S, Hughes C, Caterson B, van den Berg WB. The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis. Arthritis Rheum. 2010 Mar;62(3):647-57. Review. PubMed PMID: 20187160. 

60.   Chai LY, van de Veerdonk F, Marijnissen RJ, Cheng SC, Khoo AL, Hectors M, Lagrou K, Vonk AG, Maertens J, Joosten LA, Kullberg BJ, Netea MG. Anti-Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity. Immunology. 2010 May;130(1):46-54. Epub 2009 Dec 2. PubMed PMID: 20002791; PubMed Central PMCID: PMC2855792. 

61.   Glasson SS, Chambers MG, Van Den Berg WB, Little CB. The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse. Osteoarthritis Cartilage. 2010 Oct;18 Suppl 3:S17-23. PubMed PMID: 20864019. 

62.   Heinhuis B, Koenders MI, van de Loo FA, van Lent PL, Kim SH, Dinarello CA, Joosten LA, van den Berg WB. IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of  TLR-2 and NOD2. Ann Rheum Dis. 2010 Oct;69(10):1866-72. Epub 2010 May 14. PubMed PMID: 20472585. 

63.   Ibáñez L, Alcaraz MJ, Maicas N, Guede D, Caeiro JR, Koenders MI, van den Berg WB, Ferrándiz ML. Up-Regulation of the Inflammatory Response by Ovariectomy in Collagen-Induced Arthritis. Effects of Tin Protoporphyrin IX. Inflammation. 2010 Nov 3. [Epub ahead of print] PubMed PMID: 21046213. 

64.   Joosten LA, Netea MG, Mylona E, Koenders MI, Malireddi RK, Oosting M, Stienstra R, van de Veerdonk FL, Stalenhoef AF, Giamarellos-Bourboulis EJ, Kanneganti TD, van der Meer JW. Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis. Arthritis Rheum. 2010 Nov;62(11):3237-48. doi: 10.1002/art.27667. PubMed PMID: 20662061; PubMed Central PMCID: PMC2970687. 

65.   Kalff KM, El Mouedden M, van Egmond J, Veening J, Joosten L, Scheffer GJ, Meert T, Vissers K. Pre-treatment with capsaicin in a rat osteoarthritis model reduces the symptoms of pain and bone damage induced by monosodium iodoacetate. Eur J Pharmacol. 2010 Sep 1;641(2-3):108-13. Epub 2010 Jun 9. PubMed PMID: 20538089. 

66.   Koenders MI, van den Berg WB. Translational mini-review series on Th17 cells: are T helper 17 cells really pathogenic in autoimmunity? Clin Exp Immunol. 2010 Feb;159(2):131-6. Epub 2009 Nov 11. Review. PubMed PMID: 19912250; PubMed Central PMCID: PMC2810381. 

67.   Maicas N, Ferrándiz ML, Devesa I, Motterlini R, Koenders MI, van den Berg WB, Alcaraz MJ. The CO-releasing molecule CORM-3 protects against articular degradation in the K/BxN serum transfer arthritis model. Eur J Pharmacol. 2010 May 25;634(1-3):184-91. Epub 2010 Feb 23. PubMed PMID: 20184873.

68.   Plantinga TS, Fransen J, Takahashi N, Stienstra R, van Riel PL, van den Berg WB, Netea MG, Joosten LA. Functional consequences of DECTIN-1 early stop codon polymorphism Y238X in rheumatoid arthritis. Arthritis Res Ther. 2010;12(1):R26. Epub 2010 Feb 16. PubMed PMID: 20158887; PubMed Central PMCID: PMC2875660. 

69.   Polzer K, Joosten L, Gasser J, Distler JH, Ruiz G, Baum W, Redlich K, Bobacz K, Smolen JS, van den Berg W, Schett G, Zwerina J. Interleukin-1 is essential for systemic inflammatory bone loss. Ann Rheum Dis. 2010 Jan;69(1):284-90. Epub . PubMed PMID: 19196726. 

70.   Poole R, Blake S, Buschmann M, Goldring S, Laverty S, Lockwood S, Matyas J, McDougall J, Pritzker K, Rudolphi K, van den Berg W, Yaksh T. Recommendations for the use of preclinical models in the study and treatment of osteoarthritis. Osteoarthritis Cartilage. 2010 Oct;18 Suppl 3:S10-6. PubMed PMID: 20864015. 

71.   Stienstra R, Joosten LA, Koenen T, van Tits B, van Diepen JA, van den Berg SA, Rensen PC, Voshol PJ, Fantuzzi G, Hijmans A, Kersten S, Müller M, van den Berg WB, van Rooijen N, Wabitsch M, Kullberg BJ, van der Meer JW, Kanneganti T, Tack CJ, Netea MG. The inflammasome-mediated caspase-1 ctivation controls adipocyte differentiation and insulin sensitivity. Cell Metab. 2010 Dec 1;12(6):593-605. PubMed PMID: 21109192. 

72.   Toh ML, Gonzales G, Koenders MI, Tournadre A, Boyle D, Lubberts E, Zhou Y, Firestein GS, van den Berg WB, Miossec P. Role of interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression. PLoS One. 2010 Oct 15;5(10):e13416. PubMed PMID: 20976214; PubMed Central PMCID: PMC2955522.

73.   van de Veerdonk FL, Marijnissen R, Joosten LA, Kullberg BJ, Drenth JP, Netea MG, van der Meer JW. Milder clinical hyperimmunoglobulin E syndrome phenotype is associated with partial interleukin-17 deficiency. Clin Exp Immunol. 2010 Jan;159(1):57-64. Epub 2009 Oct 30. PubMed PMID: 19878510; PubMed Central PMCID: PMC2802694. 

74.   van Lent PL, Grevers LC, Schelbergen R, Blom A, Geurts J, Sloetjes A, Vogl T, Roth J, van den Berg WB. S100A8 causes a shift toward expression of activatory Fcγ receptors on macrophages via toll-like receptor 4 and regulates Fcγ receptor expression in synovium during chronic experimental arthritis. Arthritis Rheum. 2010 Nov;62(11):3353-64. doi: 10.1002/art.27654. PubMed PMID: 20662072. 

75.   Veenbergen S, Smeets RL, Bennink MB, Arntz OJ, Joosten LA, van den Berg WB, van de Loo FA. The natural soluble form of IL-18 receptor beta exacerbates collagen-induced arthritis via modulation of T-cell immune responses. Ann Rheum Dis. 2010 Jan;69(1):276-83. Epub . PubMed PMID: 19188194. 

76.   Santegoets K, van Bon L, Wenink M, van den Berg WB: Antigen-presenting cells and their Fcγ and Toll-like receptors: Leading suspects in autoimmunity. The Open Arthritis Journal, 3: 37-46, 2010. 

77.   Krönke G, Uderhardt S, Kim KA, Stock M, Scholtysek C, Zaiss MM, Surmann-Schmitt C, Luther J, Katzenbeisser J, David JP, Abdollahi-Roodsaz S, Tran K, Bright JM, Binnerts ME, Akhmetshina A, Böhm C, Distler JH, Joosten LA, Schett G, Abo A. R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway. Arthritis Rheum. 2010 Aug;62(8):2303-12.PubMed PMID: 20506554 

78.   Keeney M, van den Beucken JJ, van der Kraan PM, Jansen JA, Pandit A. The ability of a collagen/calcium phosphate scaffold to act as its own vector for gene delivery and to promote bone formation via transfection with VEGF(165). Biomaterials. 2010 Apr;31(10):2893-902. Epub 2009 Dec 30. PubMed PMID: 20044134. 

79.   van der Heide HJ, van der Kraan PM, Rijnberg WJ, Buma P, Schreurs BW. Elevated levels of numerous cytokines in drainage fluid after primary total hip arthroplasty. Int Orthop. 2010 Dec;34(8):1099-102. Epub 2009 Aug 21. PubMed PMID: 19693496. 

80.   van der Kraan PM. Osteoarthritis and a high-fat diet: the full 'OA syndrome' in a small animal model. Arthritis Res Ther. 2010;12(4):130. Epub 2010 Jul 28. PubMed PMID: 20701740; PubMed Central PMCID: PMC2945034. 

81.   van der Kraan PM, Blaney Davidson EN, van den Berg WB. A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis. Arthritis Res Ther. 2010;12(1):201. Epub 2010 Jan 29. Review. PubMed PMID: 20156325; PubMed Central PMCID: PMC2875624. 

82.   van der Kraan PM, Davidson EN, van den Berg WB. Bone morphogenetic proteins and articular cartilage: To serve and protect or a wolf in sheep clothing's? Osteoarthritis Cartilage. 2010 Jun;18(6):735-41. Epub 2010 Mar 6. Review. PubMed PMID: 20211748.